Daily monitoring of blood pressure in the study of current hypertension icon

Daily monitoring of blood pressure in the study of current hypertension




НазваDaily monitoring of blood pressure in the study of current hypertension
Дата28.08.2012
Розмір5.46 Kb.
ТипДокументи

Daily monitoring of blood pressure in the study of current hypertension

Al-Hashimi Sadad Khalaf Thamir, V.I. Sheiko
Luhansk Taras Shevchenko National University, Department of Anatomy and Human and Animal Physiology

Cardiovascular diseases remain the leading cause of mortality and disability of the population worldwide. Hypertension is an important modifiable risk factors of cardiovascular disease at all stages of development, regardless of gender or age. Hypertension is a powerful but potentially avoidable risk factor that has a significant impact on morbidity and mortality due to cerebrovascular disease. Hypertension is regarded as polietiologicheskoe disease in which none of the existing theories of pathogenesis is not fully explain all the causes of high blood pressure. The end of the XX century was marked not only the rapid development of fundamental ideas about high blood pressure, but also a critical revision of some provisions of the causes, mechanisms of development and treatment of this disease.
One of the factors that determine prognosis in hypertensive patients with high risk of vascular accidents (myocardial infarction, stroke), is the increased variability in average blood pressure (VAD). Increased VAD closely correlated with the severity of left ventricular remodeling, the severity of retinopathy, serum creatinine levels. Found a significant increase in systolic and diastolic blood pressure in hypertensive patients with different variants of the flow, there were differences both in terms of average pressure, so day and night.
In a study of clinical features in patients with high blood pressure is taken 120 patients with essential hypertension (EH) with stable (40 patients) and complicated course hypertensive crises (42 people), microalbuminuria (38chel), control group consisted of 25 persons. practically healthy living in the area.
Particularly marked changes in the groups with uncomplicated and complicated hypertension, the degree of reduction in systolic blood pressure (12,3 ± 0,86%, 10,0 ± 1,18% and 4,18 ± 1,27% in the control 16,3 ± 0 and 86% respectively, p <0.01). These differences were found in hypertensive patients with non-complicated course for systolic blood pressure compared with normal, day-time 149,21 ± 2,3 mm Hg (p <0.05) differences are highly significant in complicated arterial pressure (151,45 ± 2,10 mm Hg and 160,55 ± 2,35 mm Hg, p <0.01). The degree of nocturnal blood pressure significantly lower in hypertensive patients with microalbuminuria (4.18 + 1.27%, p <0.001, in crises, 10.0 + 1.18% (p <0.01) and complicated course - 12.3 0.86 mm Hg)
Increase in diastolic blood pressure was similar.
The mean diastolic blood pressure was normal for the first
Group-86, 71 1.30 mm Hg (p <0.05) higher in the group with hypertensive crises (99.7 1.4 mm Hg, p <0.01) and highly significantly increased in hypertensive patients with microalbuminuria -121.7 1.9 mm Hg (p <0.001). Daytime diastolic blood pressure in patients with microalbuminuria exceeded the control group to 27.5% (p <0.01), with crises in 26.2% (p <0.05) and was insignificant in patients without complications in 11.2% (p> 0.05).
The degree of nocturnal decline was greatest in patients of group 1 (12.8 1.19%), lowest in group 3 (with microalbuminuria, 6.98 1.04, P <0.01).
The most pronounced changes in the degree of reduction in systolic blood pressure were observed in patients with arterial hypertension complicated by crises. This is reflected in the significant decrease in the degree of reduction in night 3 times, morning, rising by 23.4% compared with the control group. The degree of nocturnal decline in hypertensive patients with crises was minimal at 2.5 times lower than in hypertensive patients without crises.
For diastolic blood pressure, these indicators were less pronounced and accounted for 42.2%.
Special attention when analyzing the performance SMAD deserve the morning, because at this time compared to other periods of the day recorded the greatest number of cardiovascular complications.

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