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ЗмістAssignments for self-knowledge, entry-level skills.
Relevance of the topic: Viral infections are one of the many groups of infectious diseases, a variety of clinical course and morphology. They are highly contagious and can cause epidemics and pandemics. Knowledge of this topic is necessary for the study of viral diseases in clinical departments (Department of Infectious Diseases, Department of Pediatrics, Department of Therapy, Department of Neurology, etc.), as well as in the work of family doctors and narrow specialties for timely diagnosis of a comprehensive, rational treatment of viral diseases, clinical anatomical analysis of sectional observations.
The purpose of (total): To be able to morphological changes (macro-and microscopic) to distinguish between viral diseases (influenza, measles, hepatitis, polio, HIV infection), to their agents, pathogenesis, complications and assess the cause of death.
The specific objectives The objectives of the entry-level
Be able to:
In order for you to understand whether the initial level of your knowledge, skills required, we offer a number of tasks to perform.
Target number 1. The wall of the body consists of 4 layers: epithelium - pseudostratified prismatic, ciliated, in his own record contains elastic fibers, lymph follicles and some bundles of smooth muscle cells. One of the shells formed are not confined to the back of the rings of hyaline cartilage. What is the authority?
Task number 2. In bronchial biopsy revealed hydropic dystrophy patient ciliated epithelium, lymphoid cell infiltration subepithelial layer. What a shell struck the bronchus?
Task number 3. Body under microscopic examination consists of irregularly shaped, inside they are lined with a single layer of compacted epithelium. Epithelium between two adjacent cavities are predominantly capillary type vessels. For a body characterized by a structure?
Specifying № 4. Histological examination of the body, it consists of segments in which the rows of cells (beams) converging to the center, which is determined by Vienna. At the border a few cloves is an artery, Vienna and duct lined with single layer epithelium. What is the authority?
Task number 5. On cross-section body consists of white and gray matter in the form of a "butterfly". Microscopic examination of the gray matter are determined by large cells with processes, many small cells with dark nuclei and fibers. Large cells with processes in the white matter are absent. What is the authority?
Standards of responses to meet the challenges for self-examination and self-knowledge, entry-level skills: 1-1, 2-1, 3-2, 4-3, 5-2.
Information necessary to supplement your knowledge, skills can be found in the following literature:
The basic theoretical issues on which you can do the task activities:
Books for learning-skills.
After studying the material on the subject for self-mastery of the material consists of the following targets:
Test task number 1. In a study of child doctor discovered catarrhal conjunctivitis, pharyngitis, laryngotracheobronchitis, the mucous membrane of cheeks, respectively, the lower molars small, white spots, and krupnopyatnistaya papular rash on the face, trunk, extremities. Which disease correspond to the detected change?
Test task number 2. Male 27 years old died of HIV infection with AIDS. What changes detected lymph nodes?
Test task number 3. A child 7 years old, died from paralysis of respiratory muscles, histological examination of the medulla oblongata revealed severe degeneration and necrosis of nerve cells, glial proliferation and lymphoid infiltrates around the vessels in the form of "Coupling." For a disease characterized by the changes described?
Test task number 4. Child 10 years ill acutely fever to 37.6 gr. Appeared cough. At survey discovered that mucosa upper airway swollen, hyperemic, with pointlike hemorrhages covered mucus. Which correspond to the detected change in diagnosis?
Test task № 5. When opening the patient who died from influenza in the lung revealed multiple cavities of irregular shape with jagged walls of 0.5-2cm, the cavity filled with a greenish-yellowish contents. What is the complication of influenza has been a patient?
Test task number 6. Death patient trod on day 3 from onset. The autopsy revealed hemorrhagic pulmonary edema, multiple hemorrhages Punctulata in the brain, including the trunk, in the mucous and serous membranes, internal organs, degenerative changes in parenchymal organs. What form of influenza has been a patient?
Test task number 7. Patient 30 years old enrolled in the infectious disease clinic. If any of these infections are the primary containment of viral replication (gates infection) coincides with the tissue to which the virus has a tropism?
Test task number 8. The child, who overcame polio with lower paraplegia (poralichi lower limbs) died of bilateral pneumonia join. Where found typical changes of poliomyelitis histologically bodies of the dead?
Test task number 9. The young men arose a marked increase of all the lymph nodes, further lymph nodes decreased significantly. Histological examination of the lymph nodes revealed adiposis, a sharp depletion of its lymphoid tissue, preservation of the reticular cells, macrophages. What kind of disease most likely to be thinking in this case?
Test task number 10. Patient 27 years old diagnosed with HIV infection. Which cells have tropism of human immunodeficiency virus?
Test task number 11. The patient died 40 years of influenza pneumonia. Which listed traits not characteristic influenzal pneumonia?
Test task number 12. A child 5 years on the basis of clinical and morphological changes diagnosed measles. What is the gateway to infection with measles?
Test task number 13. I pebenka 5 years diagnosed catarrhal pharyngitis, laryngotracheobronchitis, the buccal mucosa whitish spots. Died from cerebral edema. The autopsy revealed focal myelin breakdown, proliferation of astrocytes and microglial cells, perivascular lymphocytic infiltrates. What kind of disease you can think of?
Test task number 14. In viral hepatitis B in liver biopsy needle was found lymphocytic infiltration of portal tracts and lobules, proliferation of Kupffer cells, vacuolar degeneration and necrosis of hepatocytes. What is the cause of damage to hepatocytes?
Test task number 15. In needle biopsy of the liver is determined by vacuolar degeneration, and moderate fat, step and bridging necrosis as porto-portal and porto-central, marked sclerosis with formation of false lobules, lymphoid histiocytic infiltration. Which surest diagnosed?
Test task number 16. In needle biopsy of the liver is determined by fatty degeneration of hepatocytes, bridging necrosis and graded, Moderate and severe sclerosis of lymph histiocytic infiltration with lymphoid follicles formation of similarity. What is the most correct diagnosis?
Test hind № 17. In men 23 years of skin found multiple nodes is bright red, soft, some wounded. Gastroscopy found in the stomach of the same node. Histologically knots diagnosed sarcoma Kaposhi. Which infection may cause the appearance of this tumor?
Methodical instructions for students on practical training "Viral infection".
To work effectively in class read "The technological map classes." Early lessons reference replies check correctness solutions homework. Then by the test control will be tested to prepare your lesson.
You should independently examine the macro-and micropreparations, to analyze the tracings to solve situational problems. Makropreparaty "Influenza pneumonia," "influenzal bronchitis," "Measles pneumonia," "The liver in Botkin's disease" learning algorithm, which is given on the first lesson of the course. At mikrofoto and micropreparations learn "influenza pneumonia", "Viral Hepatitis", "spinal cord in poliomyelitis." In this study the algorithm using macro-and micropreparations (supplement number 2). Session concludes with an analysis of the results of independent work of each student by checking the description of the test control micropreparations and learning topics.
Supplement number 1
Graf logframe themes "Viral infections"
Continued additions № 1
Continuation of application number 1
Continuation of application number 1
Supplement number 2
The algorithm of morphological diagnosis of viral infections
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