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1.0 Біологія

1

Woman applied to the medico-genetic consulting centre for information about the risk of

haemophilia in her son. Her husband has been suffering from this disease since birth.

Woman and her parents are healthy (don't have haemophilia). Is the boy likely to have the

disease in this family?

A All boys will be healthy

B All boys will be ill

C 50\% of the boys will be ill

D 25\% of the boys will be ill

E 75 \% of the boys will be ill


2

A man suffering from a hereditary disease married a healthy woman. They got 5 children,

three girls and two boys. All the girls inherited their father’s disease. What is the type of the

disease inheritance?

A Dominant, X-linked

B Autosomal recessive

C Asutosomal dominant

D Y-linked

E Recessive, X-linked


3

Electrocardiogram of a 45-year-old man showed absence of P-wave in all the leads. What

part of the conducting system is blocked?

A Sinu-atrial node

B Atrioventricular node

C Common branch of the bundle of His

D Branches of the bundle of His

E Purkinje’s fibres


4

When a patient with traumatic impairment of the brain was examined, it was discovered that

he had stopped to distinguish displacement of an object on the skin. What part of the brain

was damaged?

A Posterior central gurus

B Occipital zone of the cortex

C Parietal zone of the cortex

D Frontal central gurus

E Frontal zone


5

Different functional groups can be presented in the structure of L-amino acid’s radicals.

Identify the group that is able to form ester bond:

A -OH

B -SH

C -CONH2

D -CH3

E -NH2


6

The conjugated protein necessarily contains special component as a non-protein part.

Choose the substance that can’t carry out this function:

A HNO3

B АТP

C Thiamine pyrophosphate

D AMP

E Glucose


7

Moving of the daughter chromatids to the poles of the cell is observed in the mitotically

dividing cell. On what stage of the mitotic cycle is this cell?

A Anaphase

B Metaphase

C Telophase

D Prophase

E Interfase


8

The patient with diabetes mellitus has been delivered in hospital in the state of

unconsciousness. Arterial pressure is low. The patient has acidosis. Point substances,

which accumulation in the blood results in these manifestations:

A Ketone bodies

B Amino acids

C Monosaccharides

D High fatty acids

E Cholesterol esters


9

A 58-year-old female has undergone surgery for necrotic bowel. Despite having been treated

with antibiotics, on postoperative day 5, she develops symptoms (fever, hypotension,

tachycardia, declining urine output, and confusion) consistent with septic shock. What

hemodynamic support would be helpful?

A Fluids and Dobutamine infusion

B Dobutamine infusion

C Antibiotic administration

D Fluid administration

E Atropine administration


10

It was proved that a molecule of immature mRNA (precursor mRNA) contained more triplets

than amino acids found in the synthesized protein. The reason for that is that translation is

normally preceded by:

A Processing

B Initiation

C Reparation

D Mutation

E Replication


11

Examination of a patient revealed reduced contents of magnesium ions that are necessary for

attachment of ribosomes to the granular endoplasmatic reticulum. It is known that it causes

disturbance of protein biosynthesis. What stage of protein biosynthesis will be disturbed?

A Translation

B Transcription

C Replication

D Aminoacid activation

E Termination


12

Patient 54 year-old, 5th day after surgical operation. Blood count: Erythrocytes 3,6*1012/l,

Hemoglobin 95 g/l, Erythrocyte’s hemoglobin content (color index) 0,78; Leukocytes

16*109/l, Platelets 450*109/l Blood picture: anizocytosis, poikilocytosis, reticulocytes-

3,8%. What anemia does this patient have?

A Acute posthemorragic anemia

B Acquired hemolytic anemia

C Anemia from iron deficiency

D Hypoplastic anemia

E Chronic posthemorragic anemia


13

The patient with pneumonia was treated with antibiotics for a long period. After treatment

patient complains of frequent and watery stool, abdomenal pain. What is the reason of

intestine function disorder?

A Intestinal disbacteriosis development

B Antibiotics toxic influence on the GIT

C Autoimmune reaction development

D Bacteria toxins influence

E Hereditary enzyme defect


14

A 16 year-old patient got numerous traumas in automobile accident. Now the patient is

haning a shock. АP - 80/60 mm Hg. daily urine volume 60-80 ml. What pathogenic

mechanism leads to kidneys function violation?

A Decreased hydrostatic pressure in glomerular capillaries

B Increased osmotic pressure in glomerular capillaries

C Increased pressure in Bowman’s capsule

D Increased vasopressin blood concentration

E Trauma of the urinary bladder


15

A 46 year-old patient has complained of headache, fatigue, thirst, pains in the spine and

joints for the last 2 years. Clinically observed disproportional enlargement of hands, feet,

nose, superciliary arches. He notes that he needed to buy bigger shoes three times. What is

the main reason of such disproportional enlargement of different parts of the body?

A Cartilaginous tissue proliferation under growth hormone influence

B Increased sensitivity of the tissues to growth hormone

C Joints dystrophy development

D Increased sensitivity of the tissues to insulin

E Joints chronic inflammation development


16

A 55-year-old patient with continuing ventricular arrhythmias was admitted to the hospital. The

patient is taking timolol drops for glaucoma, daily insulin injections for diabetes mellitus, and

an ACE inhibitor for hypertension. You have decided to use phenytoin instead of

procainamide. What is the reason?

A The anticholinergic effect of procainamide would aggravate glaucoma

B The local anesthetic effect of procainamide would potentiate diabetes

C The hypertensive effects of procainamide would aggravate the hypertension

D The local anesthetic effect of procainamide would aggravate the hypertension

E The cholinergic effects of procainamide would aggravate the diabetes


17

A 25-year-old woman with red and itchy eczematoid dermatitis visits your office. She had a

dental procedure one day earlier with administration of a local anesthetic. There were no

other findings, although she indicated that she had a history of allergic reactions. Which of the

following drugs is most likely involved?

A Procaine

B Cocaine

C Lidocaine

D Bupivacaine

E Etidocaine


18

The CNS stimulation produced by methylxanthines, such as caffeine, is most likely due to the

antagonism of one of the following receptors:

A Adenosine receptors

B Glycine receptors

C Glutamate receptors

D GABA receptors

E Cholinergic muscarinic receptors


19

Patients with similar complaints applied to the doctor: weakness, pain in the intestines,

disorder of GIT. Examination of the faeces revealed that one patient with four nucleus cysts

should be hospitalized immidiately. For what protozoa are such cysts typical?

A Dysenteric amoeba

B Intestinal amoeba

C Balantidium

D Trichomonas

E Lamblia


20

According to the data of WHO, for about 250 mln of Earth population fall ill with malaria. This

disease is mostly spread in tropical and subtropical regions. Range of its spread falls into

the areal of the following mosquitoes:

A Anopheles

B Culex

C Aedes

D Mansonia

E Culiseta


21

Labeled aminoacids alanine and tryptophane were introducted to a mouse in order to study

localization of protein biosynthesis in its cells. Around what organellas will the accumulation

of labeled aminoacids be observed?

A Ribosomes

B Agranular endoplasmic reticulum

C Cell centre

D Lysosomes

E Golgi apparatus


22

Highly injured person gradually died. Please choose the indicator of biological death:

A Autolysis and decay in the cells

B Disarray of chemical processes

C Loss of consciousness

D Absence of palpitation

E Absence of movements


23

After breathing with poisonous steams there is an increased quantity of slime in respiratory

passages of a chemical production worker. What of respiratory tract epithelial cells participate

in mucousa moistening?

A Goblet cells

B Fibroblasts

C Endocrine cells

D Langergans cells

E Intercalated cells


24

A patient suffering from thyrotoxicosis symptoms of vegetoasthenic syndrome was revealed.

What of the following would show the histological appearance of a thyroid gland being

stimulated by thyroid-stimulating hormone (TSH)?

A Columnar-shaped follicular cells

B Decreased numbers of follicular cells

C Increased numbers of parafollicular cells

D An abundance of colloid in the lumen of the follicle

E Decreased numbers of parafollicular capillaries


25

The reason of occurrence of some diseases of an oral cavity is connected with structural

peculiarities of its mucous membrane. What morphological attributes characterize these

features?

A No muscularis mucosa, stratified squamous epithelium

B Transitional epithelium, no submucosa

C Simple columnar ciliated epithelium

D Well developed muscularis, no submucosa

E Transitional epithelium, no muscularis mucosa


26

There is the change of teeth at the 6-8-year-old children: deciduous are replaced by

permanent. What embrionic tissues are the sources of formation of permanent teeth tissues?

A Ectodermal epithelium of a tooth plate and mesenhime

B Entodermal epithelium of a tooth plate and mesenhime

C Mesodermal epithelium and mesenhime

D I, II brachial arches

E Entodermal epithelium and mesoderm


27

The B cells of endocrine portion of pancreas are selectively damaged by alloxan poisoning.

How will it be reflected in blood plasma?

A The content of sugar increases

B The content of fibrinogen decrease

C The level of sugar decreases

D The content of globulins decreases

E The content of albumins decreases


28

In some regions of South Africa there is a spread sickle-shaped cell anemia, in which

erythrocytes have shape of a sickle as a result of substitution of glutamin by valine in the

hemoglobin molecule. What is the cause of this disease?

A Gene mutation

B Disturbance of mechanisms of genetic information realization

C Crossingover

D Genomic mutations

E Transduction


29

A female patient consulted a physician about digestive disorder, extended abdominal pain.

Examination revealed drastic decrease in hemoglobin concentration. It is known from the

anamnesis that while living in the Far East the patient used to eat freshly-salted caviar. Some

relatives living with her had the similar condition. What is the most likely diagnosis?

A Diphyllobothriasis

B Echinococcosis

C Teniasis

D Trichiniasis

E Ascaridiasis


30

On autopsy of a still-born infant it is revealed heart development abnormalities: ventricles are

not separated, originates from the right part single arterial trunk. For what class of vertebrate

is such heart construction characteristic?

A Amphibian

B Fishes

C Reptiles

D Mammals

E Birds


31

If strong oxidizers get into the bloodstream, a methemoglobin is formed. It is a compound,

where iron (II) becomes iron (III). What has to be done to save the patient?

A Interchangeable hemotransfusion has to be done

B Patient has to be exposed to the fresh air

C He has to be calmed down and put to bed

D He has to be given pure oxygen

E Respiratory centers have to be stimulated


32

A 10-year-old child complains of weakness, nausea, irritability. Helminthes of white color

and 5-10 mm long were found on the underwear. On microscopy of the scrape from the

perianal folds achromic ova of the unsymmetrical form were revealed. Indicate what helminth

is parasiting on the child?

A Enterobins vermicularis

B Ascaris lumbricoides

C ancylostoma duodenalis

D Trichina

E Trichuris


33

Parents with ill child came to the infectionist. They worked in one of the Asian countries for a

long time. Child has eathy colored skin, loss of appetite, laxity, enlarged liver, spleen,

peripheral glands. What protozoan illness can this child have?

A Visceral leishmaniasis

B Balantidiasis

C Amebiasis

D Toxoplasmosis

E Lambliasis


34

White-haired, with blue eyes girl was born in healthy parents. Irritability, anxiety, troubled

sleep and feeding developed in the first months of life of the infant. What method of genetic

investigation should be used for the exact diagnosis?

A Biochemical

B Cytological

C Twin

D Genealogical

E Population-statistical


35

The calcium canals of cardiomyocytes have been blocked on an isolated rabbit's heart. What

changes in the heart's activity can happen as a result?

A Decreased rate and force of heart beat

B Decreased heart beat rate

C Decreased force of the contraction

D Heart stops in systole

E Heart stops in diastole


36

After the trauma, the patient’s right n.vagus was damaged. Which violation of the cardiac

activity is possible in this case?

A Violation of the automatism of a Kiss-Fleck node

B Violation of the automatism of a atrio-ventricular node

C Violation of a conductivity in the right auricle

D Block of a conductivity in the atrio-ventricular node

E Arrhythmia


37

In the ovary specimen colored with hematoxylin-eosin, follicle is determined where

cubic-shaped follicle epithelium cells are placed in 1-2 layers, and scarlet covering is seen

around ovocyte. Name this follicle:

A Primary

B Primordial

C Secondary

D Mature

E Atretic


38

While studing of the family tree with history of hypertrichosis (hyperhirsutism of the ear) this

sign was founded only in the men and it was inherited from father to the son. Define the type

of hypertrichosis inheritance?

A Connected with Y-chromosome

B Autosomal- recessive

C Autosomal-dominant

D Connected with Х-chromosome recessive

E Connected with Х-chromosome dominant


39

In the perianal folds of a 5-year-old girl her mother has found some white "worms" that

caused itch and anxiety in the child. The "worms" were sent to the laboratory. During

examination the physician saw white filiform helminths 0,5-1 cm long, with pointed ends,

some helminths had twisted ends. What is the most likely diagnosis?

A Enterobiasis

B Diphyllobothriasis

C Teniasis

D Ascaridiasis

E Opisthorchiasis


40

Part of the DNA chain turned about 180 degree due to gamma radiation. What type of

mutation took place in the DNA chain?

A Inversion

B Deletion

C Doubling

D Translocation

E Replication


41

46 chromosomes were revealed on karyotype examination of the 5-year-old girl. One of the

15th pair of chromosomes is longer than usual due to connected chromosome from the 21

pair. What type of mutation does this girl have?

A Translocation

B Deletion

C Inversion

D Insufficiency

E Duplication


42

A pregnant woman had been having toxicosis with severe repeated vomiting for 24 hours. In

the end of the day there appeared tetanic convulsions and fluid loss. What shift of acid-base

state caused these changes?

A Excretory alkalosis

B Gaseous alkalosis

C Gaseous acidosis

D Metabolic acidosis

E Excretory acidosis


43

Genetic structure of eukaryote is "exon-intron-exon". This structure-functional organization of

gene caused transcription peculiarities. What will be pro-i-RNA according to the schema?

A Exon-intron-exon

B Exon-exon-intron

C Exon-exon

D Intron-exon

E Exon-intron


44

Medical examination at the military registration and enlistment office revealed that a

15-year-old boy was high, with eunuchoid body proportions, gynecomastia, female pattern of

pubic hair distribution. The boy had also fat deposits on the thighs, no facial hair, high voice,

subnormal intelligence quotient. Which karyotype corresponds with this disease?

A 47, XXY

B 45, XO

C 46, XX

D 46, XY

E 47, XXX


45

RNA that contains AIDS virus penetrated into a leukocyte and by means of reverse

transcriptase forced a cell to synthetize a viral DNA. This process is based upon:

A Reverse transcription

B Operon repression

C Reverse translation

D Operon depression

E Convariant replication


46

According to the model of double DNA helix that was suggested by Watson and Creek, it was

established that one of chains would not be lost during replication and the second chain

would be synthesized complementary to the first one. What way of replication is it?

A Semiconservative

B Analogous

C Identical

D Dispersed

E Conservative


47

A teenager was irradiated with high radiation dose that resulted in serious damages of

lymphoid system, lysis of many lymphocytes. Restoration of normal hemogram is possible

due to the functioning of the following gland:

A Thymus

B Thyroid

C Liver

D Pancreas

E Adrenal


48

It was revealed that T-lymphocytes were affected by HIV. Virus enzyme - reverse transcriptase

(RNA-dependent DNA polymerase) - catalyzes the synthesis of:

A DNA on the matrix of virus mRNA

B Virus informational RNA on the matrix of DNA

C DNA on virus ribosomal RNA

D Viral DNA on DNA matrix

E mRNA on the matrix of virus protein


49

A patient after pathological process has a thickened alveolar membrane. The direct

consequence of the process will be the reduction of:

A Diffuse lung capacity

B Oxygen capacity of blood

C Minute respiratory capacity

D Alveolar lung ventilation

E Reserve expiratiory capacity


50

Autopsy of a newborn boy revealed polydactylia, microcephalia, cheiloschisis and

uranoschisis as well as hypertrophy of parenchimatous organs. These defects correspond

with the description of Patau's syndrome. What is the most probable cause of this pathology?

A Trisomy of the 13th chromosome

B Trisomy of the 18th chromosome

C Trisomy of the 21st chromosome

D Nondisjunction of sex chromosomes

E Partial monosomy


51

An ovary specimen stained by hematoxylin-eosin presents a follicle, where cells of follicular

epithelium are placed in 1-2 layers and have cubic form, there is a bright-red membrane

around the ovocyte. What follicle is it?

A Primary

B Primordial

C Secondary

D Mature

E Atretic


52

A patient has symptoms of inflammation of urogenital tracts. Examination of a vaginal smear

revealed big monocellular, pear-shaped organisms with the pointed spike at the posterior

end of body, big nucleus and undulating membrane. What protozoa were found in the smear?

A Trichomonas vaginalis

B Trichomonas hominis

C Trichomonas buccalis

D Trypanosoma gambiense

E Lamblia intestinalis


53

During regular examination of schoolchildren it was revealed that a 10 year old girl had

asymmetric oval eggs with a larva in the scrape from her perianal folds. What diagnosis

should be made?

A Enterobiasis

B Ascariasis

C Amebiasis

D Trichocephalosis

E Ankylostomiasis


54

A woman delivered a dead child with multiple developmental defects. What protozoan

disease might have caused the intrauterine death?

A Toxoplasmosis

B Leishmaniasis

C Malaria

D Amebiasis

E Lambliasis


55

Tuberculosis can be treated by means of combined chemotherapy that includes substances

with different mechanisms of action.What antituberculous medication inhibits transcription of

RNA into DNA in mycobacteria?

A Rifampicin

B Isoniazid

C Streptomycin

D Ethionamide

E Para-aminosalicylic acid


56

A patient experienced a sudden temperature rise up to 39oС. After 6 hours the

temperature normalized. On the 2-nd day the attack recurred: in the period of paroxysm the

temperature reached 41oС, apyrexial period began after 8 hours. What type of

temperature profile is it?

A Intermitting

B Recurrent

C Hectic

D Septic

E Continued


57

Larvae were detected occasionally on the microscopic examination of the sputum of the

patient with pneumonia. Eosinophiles were detected on the blood examination. What

helminthiasis can be diagnosed?

A Ascariasis

B Enterobiosis

C Trichocephaliasis

D Paragonimiasis

E Opistorchis


58

You are studying functioning of a bacteria operon. The operator gene has been released from

the repressor gene. Immediately after this the following process will start in the cell:

A Transcription

B Translation

C Replication

D Processing

E Repression


59

While studying maximally spiralized chromosomes of human karyotype the process of cell

division was stopped in the following phase:

A Metaphase

B Prophase

C Interphase

D Anaphase

E Telophase


60

It is known that the gene responsible for development of blood groups according to AB0

system has three allele variants. If a man has IV blood group, it can be explained by the

following variability form:

A Combinative

B Mutational

C Phenotypic

D Genocopy

E Phenocopy


61

A patient complains of pain in the area of his liver. Duodenal intubation revealed yellowish,

oval, narrowed at the poles eggs with an operculum at the end. Size of these eggs is the

smallest among all helminth eggs. What is the most probable diagnosis?

A Opisthorchosis

B Teniasis

C Beef tapeworm infection

D Echinococcosis

E Diphyllobothriasis


62

A patient consulted an urologist about pain during urination. Analysis of his urine taken in the

daytime revealed eggs with a characteristic sharp point. It is known from the anamnesis that

the patient has recently returned from Australia. What is the most likely diagnosis?

A Urogenital schistosomiasis

B Intestinal schistosomiasis

C Japanese schistosomiasis

D Opisthorchiasis

E Dicroceliasis


63

A child complains of general weakness, loss of appetite, a troubled sleep, itching in the

perianal area. The provisional diagnosis is enterobiasis. In order to specify this diagnosis it

is necessary to perform:

A Scraping from perianal folds

B Roentgenoscopy

C Biopsy of muscle tissue

D Immune diagnostics

E Duodenal contents analysis


64

The cell of the laboratory animal was overdosed with Roentgen rays. As a result albuminous

fragments formed in the cytoplasm. What cell organoid will take part at their utilization?

A Lysosomes

B Golgi complex

C Ribosome

D Endoplasmic reticulum

E Cells centre


65

In course of practical training students studied a stained blood smear of a mouse with

bacteria phagocyted by leukocytes. What cell organella completes digestion of these

bacteria?

A Lisosomes

B Mytochondrions

C Granular endoplasmic reticulum

D Golgi apparatus

E Ribosomes


66

A woman with ІІІ (B), Rh- blood group born a child with ІІ (A) blood group. The

child is diagnosed with hemolytic disease of newborn as a result of rhesus incompatibility.

What blood group is the child's father likely to have?

A ІІ (A), Rh+

B I (0), Rh+

C III (B), Rh+

D I (0), Rh-

E II (A), Rh-


67

Two days after consumption of smoked pork a patient got face and eye-lid edemata,

gastrointestinal disturbances, abrupt temperature rise, muscle pain. Blood analysis showed

full-blown eosinophilia. What helminth could the patient be infected with?

A Trichina

B Pinworm

C Ascarid

D Whipworm

E Hookworm


68

A lymph node punctate of a patient with suspected protozoal disease was examined.

Examination of the stained specimen (Romanovsky's stain) revealed some crescent bodies

with pointed end, blue cytoplasm and red nucleus. What protozoan were revealed in the

smears?

A Toxoplasms

B Malarial plasmodiums

C Dermotropic leishmania

D Viscerotropic leishmania

E Trypanosomes


69

The guide of the scientific expedition in India was native who always was with his dog. What

invasive diseases can be transmitted by the dog if it is the source of invasion?

A Echinococcosis

B Teniasis

C Paragonimiasis

D Dicroceliasis

E Fascioliasis


70

A patient has acne on his face. Microspcopic examination of scrapings from the affected

areas revealed living porrect vermiform arthropoda 0,2-0,5 mm large with four pairs of short

extremities in the front part of their bodies. What is the laboratory diagnosis?

A Demodicosis

B Scabies

C Myiasis

D Pediculosis

E Phthiriasis


71

A family of students who came from Africa got a child with anemia signs. The child died soon.

Examination revealed that the child's erythrocytes have abnormal semilunar shape. Specify

genotypes of the child's parents:

A Аа х Аа

B Аа х аа

C АА х АА

D аа х аа

E Аа х АА


72

Examination of cell culture got from a patient with lysosomal pathology revealed accumulation

of great quantity of lipids in the lysosomes. What of the following diseases is this disturbance

typical for?

A Tay-Sachs disease

B Gout

C Phenylketonuria

D Wilson disease

E Galactosemia


73

A 39-year-old woman has madescence in the region of mammilla, a small ulcer with

inflammatory hyperemia and cutaneous edema. Histologic examination of tissue sampling

from this area revealed in the malpighian layer of thickened epidermis atypical cells with light

and optically empty cytoplasm, with no intracellular bridges. Such cells were also found in the

orifice of big mammal gland ducts. What is the most probable diagnosis?

A Paget's disease

B Intraductal cancer

C Basal cell carcinoma

D Epidermoid cancer

E Melanocarcinoma


74

Golgi complex exports substances from a cell due to the fusion of the membrane saccule

with the cell membrane. The saccule contents flows out. What process is it?

A Exocytosis

B Endocytosis

C Active transport

D Facilitated diffusion

E All answers are false


75

A patient working at a pig farm complains about paroxysmal abdominal pain, liquid feces with

admixtures of mucus and blood, headache, weakness, fever. Examination of large intestine

revealed ulcers from 1 mm up to several cm large, feces contained oval unicellular

organisms with cilia. What disease should be suspected?

A Balantidiasis

B Amebiasis

C Toxoplasmosis

D Lambliasis

E Trichomoniasis


76

A boy found a spider with the following morphological characteristics: it is 2 cm long, has

roundish black abdomen with two rows of red spots on its dorsal side; four pairs of jointed

limbs are covered with small black hairs. What arthropod is it?

A Karakurt spider

B Scorpion

C Solpuga

D Mite

E Tarantula


77

Normal, actively dividing cells of human red bone marrow are analyzed. What number of cells'

chromosomes is typical for G1 period?

A 46

B 48

C 47

D 45

E 23


78

A man has worked in an African country for 3 years. A month after his return to Ukraine he

consulted an ophthalmologist and complained about eye ache, eyelid edema, lacrimation

and temporary visual impairment. Underneath the eye conjunctiva the doctor revealed

helminths 30-50 mm long with elongated filiform body. What diagnosis might be suspected?

A Filariasis

B Diphyllobothriasis

C Ascaridiasis

D Enterobiasis

E Trichocephaliasis


79

Life cycle of a cell includes the process of DNA autoreduplication. As a result of it

monochromatid chromosomes turn into bichromatid ones. What period of cell cycle does this

phenomenon fall into?

A S

B Go

C G1

D G2

E M


80

A 28-year-old female patient consulted a gynecologist about sterility. Examination revealed

underdeveloped ovaries and uterus, irregular menstrual cycle. Analysis of the sex chromatin

revealed 2 Barr’s bodies in most somatic cells. What chromosome disease is most likely?

A Triple X syndrome

B Edwards' syndrome

C Patau's syndrome

D Klinefelter's syndrome

E Turner's syndrome


81

A cell at the stage of mitosis anaphase was stimulated by colchicine that inhibits

chromosome separation to the poles. What type of mutation will be caused?

A Polyploidy

B Inversion

C Deletion

D Duplication

E Translocation


82

A patient in a transplantation centre underwent heart transplantation. The organ was taken

from a donor who died in a road accident. Foreign heart can be rejected as a result of

development of transplantation immunity. It is usually prevented by means of:

A Immunosuppressors

B Chemotherapy

C Ultrasound

D Enzymes

E X-ray therapy


83

Following exposure to radiation a lot of mutant cells appeared in a patient. Some time later

most of them were detected and destroyed by the following cells of the immune system:

A T-lymphocytes-killers

B Plasmoblasts

C T-lymphocytes-supressors

D B-lymphocyte

E Stem cells


84

A gynaecologist was examining a patient and revealed symptoms of genital tract

inflammation. A smear from vagina contains pyriform protozoa with a spine, flagella at their

front; there is also an undulating membrane. What disease can be suspected?

A Urogenital trichomoniasis

B Lambliasis

C Intestinal trichomoniasis

D Toxoplasmosis

E Balantidiasis


85

A boy has I (I^0I^0) blood group and his sister has IV (I^AI^B) blood group. What blood

groups do their parents have?

A II (IАI0) and III (IВI0)

B II (IАIА) and III (IВI0)

C I (I0I0) and IV (IAIB)

D III (IВI0) and IV (IAIB)

E I (I0I0) and III (IВI0)


86

For the purpose of myocardium infarction treatment a patient was injected with embryonal

stem cells derived from this very patient by means of therapeutic cloning . What

transplantation type is it?

A Autotransplantation

B Allotransplantation

C Xenotransplantation

D Isotransplantation

E Heterotransplantation


87

An alcoholic woman has born a girl with mental and physical developmental lag. Doctors

diagnosed the girl with fetal alcohol syndrome. What effect is the cause of the girl's state?

A Teratogenic

B Mutagenic

C Malignization

D Carcinogenic

E Mechanic


88

Sex chromosomes of a woman didn't separate and move to the opposite poles of a cell

during gametogenesis (meiosis). The ovum was impregnated with a normal spermatozoon.

Which chromosomal disease can be found in her child?

A Turner's syndrome

B Down's syndrome

C Patau's syndrome

D Edwards' syndrome

E Cat cry syndrome


89

Hartnup disease is caused by point mutation of only one gene which results in disturbance of

tryptophane absorption in the bowels and its resorption in the renal tubules. It is the reason

for disorder of both digestive and urination systems. What genetic phenomenon is observed

in this case?

A Pleiotropy

B Complementary interaction

C Polymery

D Codominance

E Semidominance


90

Cytogenetic examination of a patient with reproductive dysfunction revealed normal karyotype

46 ХY in some cells, but most cells have karyotype of Klinefelter's syndrome -

47 ХХY. Such cell heterogenity is called:

A Mosaicism

B Inversion

C Transposition

D Duplication

E Monomorphism


91

As a result of prophylactic medical examination a 7 year old boy was diagnosed with

Lesch-Nyhan syndrome (only boys fall ill with it). The boy's parents are healthy but his

grandfather by his mother's side suffers from the same disease. What type of disease

inheritance is it?

A Recessive, sex-linked

B Dominant, sex-linked

C Autosomal recessive

D Autosomal dominant

E Semidominance


92

A doctor revealed tissues injury on patient's scalp with localized suppurations and diagnosed

his disease as myiasis. This infestation is caused by larvae of the following insect:

A Wohlfahrt fly

B Kissing bug

C Stable fly (Stomoxys calcitrans)

D Malarial mosquito

E Mosquito

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